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Circular RNAs (circRNAs) refer to a class of circular RNA molecules found across all kingdoms of life. Studies in 2013 have suggested that circRNAs play important regulatory roles in miRNA activity. Researchers found that CDR1as circRNA acts as a miR-7 super-sponge that contains about 70 target sites from the same miR-7 at the same transcript. The other testis-specificcircRNA, sex-determining region Y (Sry), also was found as a miR-138 sponge. About-mentioned examples suggesting that miRNA sponge effects achieved by circRNA formation may be a general phenomenon. As miR-7 modulates the expression of several oncogenes, ciRS-7/miR-7 interactions may play an important roles in cancer-related pathways. This Circular RNA (circRNA) databases and resources is a compilation of databases and web portals and servers used for circRNAs. == References == circbase.org original paper 〔RNA. 2014 Nov;20(11):1666-70. doi: 10.1261/rna.043687.113. Epub 2014 Sep 18. circBase: a database for circular RNAs. Glažar P1, Papavasileiou P1, Rajewsky N2.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Circular RNA (circRNA) databases and resources」の詳細全文を読む スポンサード リンク
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